Fly into Rome and out of Venice if the fares allow it.
- Every train leg moves you north — no backtracking
- Needs an open-jaw ticket: in at Rome, out of Venice
- Ends in Venice, where hotel nights can be the priciest
The three cities are linked by frequent high-speed trains, so the trains rarely decide the route. What does: which airport you land at, whether you fly home from a different city, and how seven nights are split.
For seven nights, Rome 3 + Florence 2 + Venice 2 is a good first version to test. Then reverse it, and add a round trip that returns to Rome so you can see exactly what the shortcut costs.
Rome to Florence takes roughly 1.5 hours by high-speed train and Florence to Venice roughly 2 hours. The decision is not the train; it is which airports you use and whether you end up back where you started.
Fly into Rome, out of Venice. Two train legs, no backtracking.
The same trains the other way. Worth testing if fares into Venice or out of Rome are better.
You leave from the airport you arrived at, but need an extra train of roughly 4 hours from Venice on the last day.
The cheapest route on paper is not always the easiest one. Check these before you commit.
Flying into Rome and out of Venice avoids a roughly 4-hour train back. If the open-jaw fare is close to a round trip, it is worth testing first; if it is much higher, compare the round trip.
Rome usually needs more time than Florence or Venice, which many visitors cover in two nights each. Moving one night changes the hotel total more than it changes what you see, so compare the totals.
Florence works as a base for Tuscany day trips, and one night in Venice often covers the main sights. Add a night only where the extra time buys something you would miss.
High-speed trains run often, but the cheapest fares sell out first and station transfers add time. Pick departure times before you lock hotel check-outs.
Use your real dates and fares. The simplest route may not be the cheapest one.
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Planning note: Train times, fares and flight options change by season and operator. Check the exact schedule for your dates before finalizing hotel nights.